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Displaying all 8 drugs
Temsirolimus
Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Approved
Matched Description: … Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). …
Matched Categories: … Sirolimus and Prodrugs …
Matched Categories: … Sirolimus and Prodrugs …
Everolimus
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Description: … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian …
Cangrelor
Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Bovine type I collagen
Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons and other connective tissues. It plays a vital role in cell growth, differentiation, attachment, and migration . Often combined with other ingredients, such as fibroblasts and keratinocytes, it allows for accelerated and effective wound healing...
Approved
Matched Description: … Interestingly, bovine type I collagen has been studied as a possible endovascular stent material, and …
Sirolimus
Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island). It was first isolated and identified as an antifungal agent with potent anticandida activity; however, after its potent antitumor...
Approved
Investigational
Matched Synonyms: … Sirolimus …
Matched Name: … Sirolimus …
Matched Description: … Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces ... [A1320] Sirolimus was first approved by the FDA in 1999 for the prophylaxis of organ rejection in ... [L39292] In November 2021, albumin-bound sirolimus for intravenous injection was approved by the FDA …
Matched Categories: … sirolimus ... sirolimus ... sirolimus ... Sirolimus and Prodrugs …
Matched Products: … Sirolimus ... Gd-sirolimus …
Matched Name: … Sirolimus …
Matched Description: … Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces ... [A1320] Sirolimus was first approved by the FDA in 1999 for the prophylaxis of organ rejection in ... [L39292] In November 2021, albumin-bound sirolimus for intravenous injection was approved by the FDA …
Matched Categories: … sirolimus ... sirolimus ... sirolimus ... Sirolimus and Prodrugs …
Matched Products: … Sirolimus ... Gd-sirolimus …
Celecoxib
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Naftopidil
Naftopidil has been investigated for the treatment of Disorder of Urinary Stent.
Investigational
Matched Description: … Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. …
Succinobucol
AGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary artery disease.
Investigational
Displaying all 8 drugs